Antigen Preparation
A synthetic peptide from C-term of human MART-1 protein
Background
"Melanocyte lineage-specific protein (MART-1; melanoma antigen recognized by T cells 1) is a widely shared melanoma antigen recognized by the T lymphocytes of patients with established malignancy. This 18 kD transmembrane protein is expressed in most melanoma tumor samples and, among normal cells in melanocytes. It is a useful marker for melanocytic tumors however it is normally found in benign nevi as well. Antibodies against the antigen are used to recognize cells of melanocytic differentiation. MART-1 antibody is a superior immunohistochemical marker for the diagnosis of malignant melanoma. "
Applications/Suggested Working Dilutions
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Immunoprecipitation
2-5 µg/ml
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Flow cytometry
Not tested
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