Antigen Preparation
A recombinant protein 440-540 amino acids of human NBD1
Background
Nucleotide-binding domain 1 (NBD1) of the cystic fibrosis transmembrane conductance regulator (CFTR) is the predominant cause of cystic fibrosis. CFTR is a multi-spanning membrane protein that not only functions as a cAMP-dependent chloride channel but also interacts with other proteins to mediate ion conductance at the cell surface of lung and intestinal epithelial cells. The NBD1 antibody can be used as the nanobody for the cause of cystic fibrosis study.
Applications/Suggested Working Dilutions
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Immunoprecipitation
2-5 µg/ml
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Flow cytometry
Not tested
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