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Antigen Preparation
A recombinant protein of full length human AID.
"AID, also known as Activation-induced cytidine deaminase, an RNA-editing deaminase, is a 24 kDa enzyme that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion (in chickens, pigs, etc.), and class-switch recombination of immunoglobulin genes. It creates mutations in DNA by deamination of cytosine base, which turns it into uracil which is recognized as a thymine. AID plays a critical role during B cell development. Protein is normally expressed in germinal center B cells, its forced expression in B cells at the wrong stage of differentiation, in non-B cells, and in Escherichia coli results in enhanced mutagenesis and mutational spectra mimicking somatic hypermutation (SHM). Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). Overexpression correlates with poor prognosis in chronic lymphocytic leukemia and lymphoma"
The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
This antibody recognizes human AID protein. The other species are not tested.
This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
The antibodies are stable for 24 months from date of receipt when stored at –20oC to –70oC. The antibodies can be stored at 2oC-8oC for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Gene ID
Applications/Suggested Working Dilutions
Western Blot
0.1-1 µg/ml
0.01-0.1 µg/ml
2-5 µg/ml
2-10 µg/ml
Flow cytometry
Not tested
Order Info
Catalog #: 604-040
Lot #:
Size: 100ug/200ul
Host: Mouse
Clone: ZY201
Isotyping: IgG1/k
Applications: IHC(P), WB
Reactivity: Hu
Price: $ 245.00
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