15-Lipoxygenase 2

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Antigen Preparation
"A synthetic peptide LP YTY LDP PLI ENS VSI corresponding to the internal portion of human LOX2 protein sequence. It is identical sequence among human, mice and rat."
15-LOX-2 is a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. This catalyzes the dioxygenation of polyunsaturated fatty acids and are upregulated in human alternatively activated macrophages (AAMs) induced by Th2 cytokine interleukin-4 (IL-4) and/or interleukin-13. 15-lipoxygenases (15-LOXs) have been implicated in various macrophage functions including efferocytosis and ferroptosis. It plays an important role in cholesterol homeostasis and CCL17 production in human macrophages.
The Rabbit IgG is purified by Epitope Affinity Purification
"This antibody recognizes15-Lox-1 protein. It reacts to human, mice and rat."
This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
The antibodies are stable for 24 months from date of receipt when stored at –20oC to –70oC. The antibodies can be stored at 2oC-8oC for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Gene ID
Applications/Suggested Working Dilutions
Western Blot
0.1-1 µg/ml
0.01-0.1 µg/ml
2-5 µg/ml
2-10 µg/ml
Flow cytometry
Not tested
Order Info
Catalog #: 600-590
Lot #: See the label
Size: 100ug/200ul
Host: Rabbit
Isotyping: Rabbit IgG
Applications: IHC(P), WB
Reactivity: Hu, Ms, Rt
Price: $ 219.00
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