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C-erbB3/HER3

c-erbB3; tyrosine kinase-type cell surface receptor HER3

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Antigen Preparation

A synthetic peptide of c-erbB3 protein

Background

"c-erbB3 is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases, which comprises several related receptor tyrosine kinases that are frequently overexpressed in a variety of carcinomas. Members of this receptor family include EGFR (HER1), Neu (ErbB-2, HER2), ErbB-3 (HER3) and ErbB-4 (HER4), which form either homodimers or heterodimers upon ligand binding. C-erbB3 is overexpressed in numerous cancers, including prostate, bladder, and breast tumors. "

PURIFICATION The Rabbit IgG is purified by Epitope Affinity Purification	SPECIFICITY This antibody recognizes human C-erbB3/HER3 protein. The other species are not tested.
FORMULATION This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer	STORAGE The antibodies are stable for 24 months from date of receipt when stored at –20oC to –70oC. The antibodies can be stored at 2oC-8oC for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.

Gene ID

2065

Applications/Suggested Working Dilutions

Western Blot

0.1-1 µg/ml

ELISA

0.01-0.1 µg/ml

Immunoprecipitation

2-5 µg/ml

IHC

2-10 µg/ml

Flow cytometry

Not tested

Order Info

Catalog #:	602-540
Lot #:	See the label
Size:	100ug/200ul
Host:	Rabbit
Clone:
Isotyping:	Rabbit IgG
Applications:	IHC(P), WB
Reactivity:	Hu
Price:	$ 199.00

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