PLAC1 (Phosphospecific)
placenta-specific 1

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Product Preparation
A panel of synthetic peptides corresponding to the predicted multiple phosphorylation sites, including S121, Y147, S156. Those sequences are identical to human, rat and mouse.
The PLAC1, a placenta-specific gene, which encodes a putative cell surface protein, is highly expressed in placenta, testis, cancer cell lines and lung tumors. PLAC1 is exclusively expressed by cells of trophoblastic lineage in the mouse, and maps to a region of the X-chromosome known to be important in placenta growth. PLAC1 is also expressed in human hepatocellular cancer tissues as well as in several other types of cancer tissues and/or tumor cell lines. PLAC1 represents a new class of tumor associated antigen with restricted expression in placenta and cancer tissues, which may serve as a target for cancer vaccination. The phosphorylation of PLAC1 by kinases CDK5, PKC may be involved in tumor associated process.
The Rabbit IgG is purified by Epitope Affinity Purification
This antibody recognizes ~22 kDa of Phosphospecific PLAC1 protein. It cross-reacts to human, rat and mouse. The other species are not tested.
This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer.
The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Gene ID
Applications/Suggested Working Dilutions
Western Blot
0.1-1 µg/ml
0.01-0.1 µg/ml
2-5 µg/ml
2-10 µg/ml
Flow cytometry
5-10 µg/ml
Order Info
Catalog #: 602-990
Lot #: See the label
Size: 100 ug
Host: Rabbit
Isotyping: Rabbit IgG
Applications: ELISA, WB, IHC
Reactivity: Hu, Ms, Rt
Price: $ 355.00
Dong XY, et al. Plac1 is a tumor-specific antigen capable of eliciting spontaneous antibody responses in human cancer patients. Int J Cancer. 122(9):2038-43 (2008).
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