L1CAM(pS1152)
L1 cell adhesion molecule; CD171

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Product Preparation
N/A
Background
The cell adhesion molecule L1 (L1CAM) is an axonal glycoprotein which belongs to the immunoglobulin supergene family. The ectodomain,consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic raplegia and hydrocephalus). The malfunction of LaCAM may contribute to neurological and cancerous diseases.
PURIFICATION
The Rabbit IgG is purified by site-modified Epitope Affinity Purification.
SPECIFICITY
N/A
FORMULATION
This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer.
STORAGE
The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Gene ID
16728
Applications/Suggested Working Dilutions
Western Blot
0.1-1 µg/ml
ELISA
0.01-0.1 µg/ml
Immunoprecipitation
2-5 µg/ml
IHC
2-10 µg/ml
Flow cytometry
5-10 µg/ml
Order Info
Catalog #: 601-070
Lot #: See the label
Size: 100 ug
Host: Rabbit
Isotyping: Rabbit IgG
Applications: ELISA, WB
Reactivity: Hu/Rt/Ms
Price: $ 325.00
REFERENCES
Lane DP and EB Lane. A rapid antibody assay system for screening hybridoma cultures, J. Immunol. Methods, 47: 303-307 (1981)
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