Antigen Preparation
A synthetic peptide corresponding to the epitope of RPSYR with a single phosphorylation site Ser133.
Background
"CREB is a bZIP transcription factor that binds the cAMP response element (CRE) and activates target genes. It is involved in many extracellular signals resulting in regulation of a variety of cellular responses. Phosphorylation of CREB at Ser133 by various kinases, such as PKA, PKC, CaM kinase II and IV, is necessary for CREB signaling."
Applications/Suggested Working Dilutions
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Immunoprecipitation
2-5 µg/ml
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Flow cytometry
Not tested
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