CD72
B-cell differentiation antigen CD72; CD72 antigen

PDF Image Download Product PDF
Product Preparation
A synthetic peptide corresponding to N-term of human CD72 protein. This sequence is identical to mouse and rat.
Background
CD72 antigen is a member of the type II integral membrane glycoproteins which includes other related cell surface moleculaes such as the asialoglycoprotein receptors, CD23 and the Kupffer cell recpeotr. The function of CD72 is unknown but the exposure of B cells to CD72 antibodies activates a variety of signaling pathways and can induce MHC class II expression and B cell proliferation. CD72 antigen is expressed on all cells of B cell lineage with the exception of plasma cells and weakly on human tissue macrophages.
PURIFICATION
The Rabbit IgG is purified by Epitope Affinity Purification
SPECIFICITY
This antibody reacts with human CD72. The other species are not tested.
FORMULATION
This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
STORAGE
The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Gene ID
N/A
Applications/Suggested Working Dilutions
Western Blot
0.1-1 µg/ml
ELISA
0.01-0.1 µg/ml
Immunoprecipitation
2-5 µg/ml
IHC
2-10 µg/ml
Flow cytometry
5-10 µg/ml
Order Info
Catalog #: 500-10924
Lot #: See the label
Size: 100 ug
Host: Rabbit
Isotyping: Rabbit IgG
Applications: WB
Reactivity: Hu
Price: $ 349.00
REFERENCES
Kataoka,T.R., Kumanogoh,A., Bandara,G., Metcalfe,D.D. and Gilfillan,A.M. CD72 negatively regulates KIT-mediated responses in human mast cells. J. Immunol. 184 (5), 2468-2475 (2010)
©2011-2015 Abbomax.com. All rights reserved.