CD4
CD4 antigen; T-cell surface glycoprotein CD4; T-ce

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Product Preparation
Synthetic peptide corresponding to internal region of human CD4 protein
Background
CD4, a single-pass type I transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is an accessory protein for MHC class-II antigen/T-cell receptor interaction, and may regulate T-cell activation, induce the aggregation of lipid rafts. Upon HIV-1 binding to the cell membrane, CD4 interacts with HIV-1 envelope polyprotein gp160 and protein Vpu with presence of HIV-1 gp120.
PURIFICATION
The Rabbit IgG is purified by Epitope Affinity Purification
SPECIFICITY
N/A
FORMULATION
This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
STORAGE
The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Gene ID
920
Applications/Suggested Working Dilutions
Western Blot
0.1-1 µg/ml
ELISA
N/A
Immunoprecipitation
2-5 µg/ml
IHC
2-10 µg/ml
Flow cytometry
Not tested
Order Info
Catalog #: 500-4704
Lot #: See the label
Size: 100 ug
Host: Rabbit
Isotyping: Rabbit IgG
Applications: WB
Reactivity: Hu
Price: $ 299.00
REFERENCES
N/A
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