Antigen Preparation
"A synthetic peptide corresponding to N-term of c-Fos protein. This sequence is identical in human, mouse, rat abd bovine."
Background
"The c-Fos proto-oncogene, an 55 kDa nuclear phosphor-protein, belongs to a family of transcription factors. It plays important roles in cell proliferation and differentiation. c-Fos is associated with the c-Jun protein, forming a stable c-Fos/c-Jun heterodimeric complex, this complex binds to the DNA promoter region which regulate transcription. Expression of the c-Fos gene is low in most normal adult tissues. However, high levels of expression have been detected in normal skin."
Applications/Suggested Working Dilutions
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Immunoprecipitation
2-5 µg/ml
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Flow cytometry
Not tested
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